Ebook Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series), by Stephen M
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Ebook Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series), by Stephen M
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Stahl's Essential Psychopharmacology is intended as a primer text for this field, and can be read cover to cover by anyone from the novice to the expert. Expanded and fully revised, this third edition enlists advances in neurobiology and recent clinical developments to explain with renewed clarity the concepts underlying drug treatment of psychiatric disorders. Features of this edition are clinical advances in antipsychotic and antidepressant therapy. It includes new coverage of sleep disorders, chronic pain, and disorders of impulse control. This remains the essential text for students, scientists, psychiatrists, and other mental health professionals.
- Sales Rank: #245653 in Books
- Published on: 2008-03-17
- Original language: English
- Number of items: 1
- Dimensions: 9.96" h x 2.36" w x 6.97" l, 4.80 pounds
- Binding: Paperback
- 1132 pages
Review
"Dr. Stahl's latest edition remains the clearest book covering all the latest advances and developments in psychopharmacology. The method of teaching through illustration and conceptual form should continue to make it very popular.....Completely revised and updated with the latest developments, this editioncaptures the shift from the receptor model to brain circuits and signal transduction cascades. The basic sciences section has been doubled to cover the advances in the understanding of the functioning of neurons, signal transduction cascades, ion channels, genetics, brain circuits, imaging, and disease models of pathophysiology. The clinical section has been expanded from the previous edition to discuss the psychiatric disorder and the corresponding malfunctioning brain circuit. This section also details the advances in the latest hypothesis of the disorder as well as the latest drugs related to the treatment of the disorder. New to this edition is a chapter on pain and the treatment of fibromyalgia and other somatic syndromes. Separate chapters now cover dementia and attention deficit disorders with the newest treatments as well as drugs that are in the pipeline. Of special note is the chapter on reward that has been expanded from substance abuse to cover disorders of sexual function, eating, and impulsivity. Unique to Dr. Stahl's books are the illustrations, which have been expanded in this edition to reflect the latest advances. Information is presented in conceptual form that makes it easier to read and understand. The book maintains a consistent format and is augmented with more graphs and tables."
--Doody's Book Review Service
"Stephen Stahl is one of the most recognizable names in psychopharmacology. He is an inspiring teacher who has a knack for synthesizing complex scientific information for students, residents, psychiatrists, and nonmedical mental health practitioners....[H]e has started publishing psychopharmacology books that are not only very readable and up-to-date, but are in my opinion the most creatively illustrated texts of psychopharmacology. My trainees rave about his books and quote them often."
--Journal of Clinical Psychiatry
About the Author
Stephen M. Stahl is Adjunct Professor of Psychiatry at the University of California at San Diego. He has conducted numerous research projects awarded by the National Institute of Mental Health, the Veterans Administration, and the pharmaceutical industry. Author of more than 200 articles and chapters, Dr Stahl is an internationally recognized clinician, researcher, and teacher in psychiatry with subspecialty expertise in psychopharmacology.
Most helpful customer reviews
80 of 88 people found the following review helpful.
Good overall, but unsubtle and dodges legitimate controversies
By James E. OBrien
The biochemical illustrations are excellent but the text is lacking in nuance. (Maybe that book would require another thousand pages.) The author, in my opinion, is far too keen on a strict medical model and acceptance of DSM IV TR "disorders" and outlier conditions as diseases for which there is a pill lying in wait. The text glosses over these controversies the way that Powerpoint does at a pharma sponsored CME conference.
Nevertheless the chapter on antidepressant augmentation was excellent, though in practice I think it is foolish to use lithium for unipolar depression augmentation because it is the easiest drug to overdose on (and of course one of the big selling points of the SSRIs over TCAs to begin with was the safety factor in a suicide attempt.) One treatment that I was not aware of, and I will definitely start using in refractory cases, is MTHF supplementation which appears very safe and effective. I also learned quite a bit about alpha-2-delta ligands in the excellent chapter on ion channel blockers.
One chapter I had a lot of problems with was sleep disorders. In my opinion, the author is too cavalier about using benzo hypnotics, despite the fact that most evidence based treatment guidelines (i.e ACOEM) specifically warn against this except as a very short-term solution. I am disappointed that he failed to mention that these a history of alcohol or drug dependence changes the whole treatment paradigm. He seems enthusiastic about the "Z" hypnotics despite the scandalous promotion of Ambien as nonaddictive, a claim the manufacturer Aventis was forced to rescind. Not to mention the literature on sleepwalking and sleep driving with this drug (the Patrick Kennedy incident may have been related to this). I was also surprised to see Ambien CR (zolpidem CR) listed as a first line drug in the "hypnotic pharmacy" on page 849, under the premise of being nonaddictive. I say, fool me once, shame on you, fool me twice shame on me. In actual practice, the best move is to ditch all forms of Ambien, and go with Lunesta or even better yet, Rozerem, and only after trying a sedative antidepressant. The avoidance of these issues was curious to me, because the author did not flinch from addressing the problems and controversies with antispsychotics in that excellent chapter.
I also believe that the TCAs were given too little attention for their effectiveness in pain syndromes.
The following complaint is mostly about DSM-IV-TR which is obviously not the author's fault, but I wish he hadn't gotten so drunk on Bob Spitzer's Kool-Aid. Garbage in, garbage out, and if you are medicating a questionable diagnosis you will get questionable results or the condition will get better on its own, as it would have anyway. Many would argue that the lowering of the bar for psychiatric diagnosis in DSM (i.e. autism, ADD, Major Depression, PTSD) has been a benefit as these conditions are now more reliably diagnosed and more people are getting help. That may be true, but this has come at the expense of phenomenological validity. If you and I have dysphoria and 4 other completely different symptoms, guess what, we have the same diagnosis, so what are we really dealing with? If I "hear about" a tragic event and have some anxiety symptoms I can qualify for PTSD according to the DSM. I guess Mohammed Atta caused mental disorder in 300 million Americans. Does anyone believe that? Thirty years ago, if someone told me their kid had ADD or autism, I knew exactly what to expect. Today that child may be a moderately misbehaving child with poor social skills. As Tony Soprano once sarcastically asked a school psychologist diagnosing ADD, "What constitutes a fidget?"
All of this inclusiveness, whether the motive is compassionate or monetary, creates enormous problems in psychopharmacological comparisons. Older antidepressant and other psychopharm studies were done with severely ill patients with pure pathology. Today, the subjects may have a self-limited condition thanks to the changes in DSM. The success numbers for most of the SSRI studies are as inflated as today's home run totals in baseball and cannot be compared to the data from 25-30 years ago on TCAs and MAOIs. In other words, I don't buy a lot of the head to head comparisons and ratings in the text based on incomparable studies. Data is emerging that these are actually much more efficacious than the SSRI's which the author considers (along with the majority of psychiatrists) to be first line treatment. But let's be honest--the reason for this is defensive medicine, not because the new drugs are better. In fact, every senior psychopharmacologist knows that short of ECT, nothing works for refractory cases like Parnate, which is hardly ever used anymore. However, I do give the author of coming to the defense of MAOIs with some great illustrations about how the dietary problems with this group are completely overblown.
Despite these problems, I credit the author for a monumental undertaking. Obviously anything this prolific and robust will contain material with which some practitioners disagree. That would be no different if I had written it myself.
James O'Brien, M.D.
10 of 12 people found the following review helpful.
Excellent, informative, and utterly lacking in a few places
By Anna M. Vamvakias
Stahl's Essential Psychopharmacology is an excellent,informative tome on current medications.
That being said, the book utterly lacks any information on the differences in responses to these drugs along ethnic diversity lines, or gender differences, or interactions with commonly used herbs or supplements.
The topic of diversity and supplement usage is extremely relevant in today's world and knowledge of the these subjects will only increase our clients' comfort.
7 of 8 people found the following review helpful.
impressive
By Amazon Customer
Essential Pharmacology is comprehensive and most informative. Diagnostic subjects range from mood disorders to ADHD to Fibromyalgia. The text elucidates genetics and mechanism of action through the liberal use of cartoons which are for the most part illuminating but are at times trivial. My only complaint is the lack of information on eating disorders. Which has more to do with the general ignorance of the subject vs. an editorial neglect.
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